A comparative evaluation of some blood sugar lowering agents of plant origin

被引：127

作者：

Chattopadhyay, RR ^{[1
]}

机构：

[1] Indian Stat Inst, Biometry Res Unit, Kolkata 700035, W Bengal, India

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1999年 / 67卷 / 03期

关键词：

blood sugar lowering activity; Azadirachta indica; Gymnema sylvestre; Catharanthus roseus; Ocimum sanctum; comparative study;

D O I：

10.1016/S0378-8741(99)00095-1

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A comparison of blood sugar lowering activity of four important medicinal plants (Azadirachta indica, Gymnema sylvestre, Catharanthus roseus and Ocimum sanctum) were carried out against normal and streptozotocin-induced diabetic rat models. The plant extracts decreased the blood sugar level in varying degrees. Blood sugar lowering unit (BLU) of activity of each leaf extract and tolbutamide was calculated by ED50 values. Statistical analysis revealed significant (P < 0.05) variation among the treatments as well as doses with regard to their blood sugar lowering capacity. A. indica leaf extract was found to have the most potent blood sugar-lowering activity followed by C. roseus, G. sylvestre and O. sanctum. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：367 / 372

页数：6

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