Somatic markers and response reversal: Is there orbitofrontal cortex dysfunction in boys with psychopathic tendencies?

被引:198
作者
Blair, RJR
Colledge, E
Mitchell, DGV
机构
[1] UCL, Inst Cognit Neurosci, London WC1H 3AR, England
[2] UCL, Dept Psychol, London WC1H 3AR, England
基金
英国医学研究理事会;
关键词
amygdala; orbitofrontal cortex; psychopathic tendencies; psychopathy;
D O I
10.1023/A:1012277125119
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
This study investigated the performance of boys with psychopathic tendencies and comparison boys, aged 9 to 17 years, on two tasks believed to be sensitive to amygdala and orbitofrontal cortex functioning. Fifty-one boys were divided into two groups according to the Psychopathy Screening Device (PSD, P. J. Frick & R. D. Hare, in press) and presented with two tasks. The tasks were the gambling task (A. Bechara, A. R. Damasio. H. Damasio, & S. W. Anderson, 1994) and the Intradimensional/Extradimensional (ID/ED) shift task (R. Dias, T. W. Robbins, & A. C. Roberts, 1996). The boys with psychopathic tendencies showed impaired performance on the gambling task. However, there were no group differences on the ID/ED task either for response reversal or extradimensional set shifting. The implications of these results for models of psychopathy are discussed.
引用
收藏
页码:499 / 511
页数:13
相关论文
共 76 条
  • [1] Recognition of facial emotion in nine individuals with bilateral amygdala damage
    Adolphs, R
    Tranel, D
    Hamann, S
    Young, AW
    Calder, AJ
    Phelps, EA
    Anderson, A
    Lee, GP
    Damasio, AR
    [J]. NEUROPSYCHOLOGIA, 1999, 37 (10) : 1111 - 1117
  • [2] Impaired declarative memory for emotional material following bilateral amygdala damage in humans
    Adolphs, R
    Cahill, L
    Schul, R
    Babinsky, R
    [J]. LEARNING & MEMORY, 1997, 4 (03) : 291 - 300
  • [3] Impairment of social and moral behavior related to early damage in human prefrontal cortex
    Anderson, SW
    Bechara, A
    Damasio, H
    Tranel, D
    Damasio, AR
    [J]. NATURE NEUROSCIENCE, 1999, 2 (11) : 1032 - 1037
  • [4] Startle reflex and emotion modulation impairment after a right amygdala lesion
    Angrilli, A
    Mauri, A
    Palomba, D
    Flor, H
    Birbaumer, N
    Sartori, G
    diPaola, F
    [J]. BRAIN, 1996, 119 : 1991 - 2000
  • [5] ANISKIEWICZ AS, 1979, J CLIN PSYCHOL, V35, P60, DOI 10.1002/1097-4679(197901)35:1<60::AID-JCLP2270350106>3.0.CO
  • [6] 2-R
  • [7] The importance of callous-unemotional traits for extending the concept of psychopathy to children
    Barry, CT
    Frick, PJ
    DeShazo, TM
    McCoy, MG
    Ellis, M
    Loney, BR
    [J]. JOURNAL OF ABNORMAL PSYCHOLOGY, 2000, 109 (02) : 335 - 340
  • [8] Emotion, decision making and the orbitofrontal cortex
    Bechara, A
    Damasio, H
    Damasio, AR
    [J]. CEREBRAL CORTEX, 2000, 10 (03) : 295 - 307
  • [9] Bechara A, 1998, J NEUROSCI, V18, P428
  • [10] INSENSITIVITY TO FUTURE CONSEQUENCES FOLLOWING DAMAGE TO HUMAN PREFRONTAL CORTEX
    BECHARA, A
    DAMASIO, AR
    DAMASIO, H
    ANDERSON, SW
    [J]. COGNITION, 1994, 50 (1-3) : 7 - 15