Crown ether catalyzed stereospecific synthesis of Z- and E-stilbenes by Wittig reaction in a solid-liquid two-phases system

被引:49
作者
Bellucci, G [1 ]
Chiappe, C [1 ]
LoMoro, G [1 ]
机构
[1] UNIV PISA,DIPARTIMENTO CHIM BIOORGAN,I-56126 PISA,ITALY
关键词
D O I
10.1016/0040-4039(96)00802-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Potassium hydroxide and a catalytic amount of 18-crown-6 are used, in alternative to the classical Wittig conditions, to prepare very rapidly and stereoselectively Z- and E-stilbenes. In particular, the use of benzyltriphenylphosphonium iodides always leads to a complete Z-stereospecificity, while benzyldiphenylchlorophosphonium salts give a complete E-stereospecificity. (C) 1996 Elsevier Science Ltd
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页码:4225 / 4228
页数:4
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