Community- and individual-level determinants of Wuchereria bancrofti infection in Leogane Commune, Haiti

被引:13
作者
Boyd, HA
Waller, LA
Flanders, WD
Beach, MJ
Sivilus, JS
Lovince, R
Lammie, PJ
Addiss, DG
机构
[1] Ctr Dis Control & Prevent, Chamblee Facil, Div Parasit Dis, Atlanta, GA 30341 USA
[2] Emory Univ, Rollins Sch Publ Hlth, Dept Epidemiol, Atlanta, GA 30322 USA
[3] Emory Univ, Rollins Sch Publ Hlth, Dept Biostat, Atlanta, GA 30322 USA
[4] Hop St Croix, Leogane, Haiti
关键词
D O I
10.4269/ajtmh.2004.70.266
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
We conducted a school-based assessment of the geographic distribution of Wuchereria bancrofti infection in Leogane Commune, Haiti, using the immunochromatographic test. In multivariate analyses performed using generalized linear mixed models, children attending schools in the foothills and plains were 3.95 (95% confidence interval [CI] = 1.28-12.23) and 23.56 (95% CI = 8.99-61.79) times as likely to be infected, respectively, as children attending mountain schools. Infection prevalence decreased with increasing altitude, but some local foci of infection were detected at higher altitudes. Higher school tuition, a marker of socioeconomic status (SES), was not associated with decreased infection prevalence. Our results indicate that although the force of infection in Leogane Commune is greatest below 70 meters above sea level, higher altitude communities are not exempt from infection. Lymphatic filariasis (LF) elimination programs should consider extending infection mapping activities to presumed non-LF altitudes. In addition, higher SES does not confer protection against W. bancrofti infection.
引用
收藏
页码:266 / 272
页数:7
相关论文
共 14 条
[1]   Random-effects modeling of categorical response data [J].
Agresti, A ;
Booth, JG ;
Hobert, JP ;
Caffo, B .
SOCIOLOGICAL METHODOLOGY 2000, VOL 30, 2000, 30 :27-80
[2]  
[Anonymous], RES RAP GEOGR ASS BA
[3]   APPROXIMATE INFERENCE IN GENERALIZED LINEAR MIXED MODELS [J].
BRESLOW, NE ;
CLAYTON, DG .
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 1993, 88 (421) :9-25
[4]   SOCIAL AND ECONOMIC-FACTORS AND THE CONTROL OF LYMPHATIC FILARIASIS - A REVIEW [J].
EVANS, DB ;
GELBAND, H ;
VLASSOFF, C .
ACTA TROPICA, 1993, 53 (01) :1-26
[5]   ELEPHANTIASIS - A DISEASE OF DEVELOPMENT IN NORTH-EAST GHANA [J].
HUNTER, JM .
SOCIAL SCIENCE & MEDICINE, 1992, 35 (05) :627-649
[6]  
Littell R.C., 1996, SAS SYSTEM MIXED MOD, P423
[7]   Re-assessing the global prevalence and distribution of lymphatic filariasis [J].
Michael, E ;
Bundy, DAP ;
Grenfell, BT .
PARASITOLOGY, 1996, 112 :409-428
[8]   Lymphatic filariasis elimination: progress in global programme development [J].
Molyneux, DH ;
Zagaria, N .
ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, 2002, 96 :S15-S40
[9]   Lymphatic filariasis in Uganda: baseline investigations in Lira, Soroti and Katakwi districts [J].
Onapa, AW ;
Simonsen, PE ;
Pedersen, EM ;
Okello, DO .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2001, 95 (02) :161-167
[10]   EFFICIENT ASSESSMENT OF FILARIASIS ENDEMICITY BY SCREENING FOR FILARIAL ANTIGENEMIA IN A SENTINEL POPULATION [J].
RAMZY, RMR ;
HAFEZ, ON ;
GAD, AM ;
FARIS, R ;
HARB, M ;
BUCK, AA ;
WEIL, GJ .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1994, 88 (01) :41-44