PEDOT/MWCNT composite film coated microelectrode arrays for neural interface improvement

被引:74
作者
Chen, Sanyuan [1 ]
Pei, Weihua [1 ]
Gui, Qiang [1 ]
Tang, Rongyu [1 ]
Chen, Yuanfang [1 ]
Zhao, Shanshan [1 ]
Wang, Huan [1 ]
Chen, Hongda [1 ]
机构
[1] Chinese Acad Sci, Inst Semicond, State Key Lab Integrated Optoelect, Beijing 100083, Peoples R China
基金
中国国家自然科学基金;
关键词
Microelectrode arrays; PEDOT/MWCNT; Electrodeposition; Charge injection limit; Neural interface; CARBON NANOTUBE; ELECTRODE; MONOLAYER; ADHESION;
D O I
10.1016/j.sna.2013.01.033
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
080906 [电磁信息功能材料与结构]; 082806 [农业信息与电气工程];
摘要
High-performance electrode materials play a crucial role at the interface of implantable neural electrode. To realize bidirectional transduction between neural tissue and neural microelectrodes, the electrode material must satisfy the function of stimulating and recording. As the number and density of electrode increase, tiny electrodes with high performance are needed in future bioengineering study. In this study, a method of electrochemically co-deposited poly(3,4-ethylenedioxythiophene)/multi-walled carbon nanotube (PEDOT/MWCNT) onto microelectrode arrays with 8 channels was investigated. After modification, the impedance, charge transfer ability and frequency response characteristic were improved simultaneously. Compared with bare golden electrode, the coated microelectrodes with a surface area of 615 mu m(2) exhibited a particularly high safe charge injection limit of 7.74 mC/cm(2) and low impedance of 12 k Omega at 1 kHz. In vivo inferior colliculus implantation of rats revealed that the composite film coated microelectrodes showed higher signal to noise ratio recordings >15 dB compared to 6 dB SNR of bare gold microelectrodes. (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码:141 / 148
页数:8
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