sox30:: a novel zebrafish sox gene expressed in a restricted manner at the midbrain-hindbrain boundary during neurogenesis

被引:36
作者
De Martino, SP
Errington, F
Ashworth, A
Jowett, T
Austin, CA
机构
[1] Univ Newcastle, Sch Med, Sch Biochem & Genet, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
[2] Inst Canc Res, Chester Beatty Labs, London SW3 6JB, England
关键词
sox; zebrafish; development; brain; midbrain-hindbrain boundary;
D O I
10.1007/s004270050264
中图分类号
Q2 [细胞生物学];
学科分类号
071009 [细胞生物学]; 090102 [作物遗传育种];
摘要
The Sox family of proteins is thought to act to regulate gene expression in a wide variety of developmental processes. Here we describe the cloning of sox30, a novel sox gene from the zebrafish (Danio rerio). In situ hybridization shows that sox30 is expressed in a restricted manner at the boundary between the midbrain and hindbrain during nervous system development. This expression pattern is in direct contrast to that of most other neuronally expressed Sox genes which are expressed throughout the nervous system.
引用
收藏
页码:357 / 362
页数:6
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