Role of flow cytometry in the diagnosis of lymphadenopathy in children

被引：14

作者：

Chen, Y ^{[1
]}

Savargaonkar, P ^{[1
]}

Fuchs, A ^{[1
]}

Wasserman, P ^{[1
]}

机构：

[1] Long Isl Jewish Med Ctr, Dept Pathol, New Hyde Pk, NY 11040 USA

来源：

DIAGNOSTIC CYTOPATHOLOGY | 2002年 / 26卷 / 01期

关键词：

fine-needle aspiration; flow cytometry; pediatric lymphadenopathy;

D O I：

10.1002/dc.10027

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

To evaluate the combination of fine-needle aspiration (FNA) and flow cytometric immunophenotyping (FCI) in the diagnosis of lymphadenopathy in children, we reviewed a total of 71 FNA specimens from pediatric patients with persistent lymphadenopathy. Two cases were deemed inadequate. In the remaining 69 cases, 54 (78%) were diagnosed as benign lesions, 9 (13%) as Hodgkin's lymphoma, 4 (6%) as non-Hodgkin's lymphoma or leukemic infiltrate, and 2 as metastatic tumors. Of the 69 cases, 25 cases (38%) were diagnosed based on cytomorphology alone 30 (43%) by combined cytomorphology and FCI, and 19 (28%) by surgical biopsy. In conclusion, FNA is an easy, safe, and reliable procedure in the diagnosis of lymphadenopathy in children, In difficult cases, FCI can be used to exclude non-Hodgkin's lymphomas. (C) 2002 Wiley-Liss, Inc.

引用

页码：5 / 9

页数：5

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