Convenient and efficient stereoselective synthesis of (2Z)-2(chloromethyl)alk-2-enoates using iron(III) or indium(III) chloride

被引：41

作者：

Das, B ^{[1
]}

Banerjee, J ^{[1
]}

Ravindranath, N ^{[1
]}

Venkataiah, B ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Organ Chem Div 1, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 11期

关键词：

(2Z)-2-(chloromethyl)alk-2-enoates; Baylis-Hillman adducts; 3-hydroxy-2-methylene-alkanoates; FeCl3; InCl3;

D O I：

10.1016/j.tetlet.2004.01.101

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The stereoselective synthesis of (2Z)-2-(chloromethyl)alk-2-enoates has been achieved efficiently and in high yields and in short reaction times from Baylis-Hillman adducts, 3-hydroxy-2-methylene-alkanoates, by treatment with FeCl3 or InCl3 at room temperature. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：2425 / 2426

页数：2

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