Cerebrovascular pathology in Alzheimer's disease: Cause, effect or epiphenomenon?

被引：61

作者：

Hachinski, V

Munoz, DG

机构：

来源：

CEREBROVASCULAR PATHOLOGY IN ALZHEIMER'S DISEASE | 1997年 / 826卷

关键词：

D O I：

10.1111/j.1749-6632.1997.tb48456.x

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Cerebrovascular pathology abounds in Alzheimer's disease. Changes in the endothelium, disruption of the blood-brain barrier and amyloid deposition in the cerebral blood vessels are almost universal in advanced cases. Do these changes represent the cause, the effect, or the consequences of a common pathogenesis of Alzheimer's disease? This volume addresses some of these issues by presenting new knowledge gained from a diversity of fields. Recognition of the mechanisms involved will open new possibilities for therapeutic trials.

引用

页码：1 / 6

页数：6

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