HLA-B27 and HLA-B73 polymorphism and its role on antigenicity, peptide presentation, and disease susceptibility

被引：6

作者：

DeCastro, JAL

机构：

来源：

CLINICAL RHEUMATOLOGY | 1996年 / 15卷

关键词：

HLA-B27; HLA-B73; spondyloarthropathies; antigen presentation; T-cell recognition;

D O I：

10.1007/BF03342650

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Current ideas on the structure, evolution, and disease association of HLA-B27 antigens are presented, with emphasis on the effect of HLA-B27 polymorphism on T-cell recognition and antigen-presenting properties of these molecules. The molecular relationship between HLA-B27 and HLA-B73, and its implications for a putative pathogenetic role of the later antigen are discussed.

引用

收藏

页码：67 / 71

页数：5

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