Application of the Grubbs ring-closure olefin metathesis in the synthesis of trans-fused oxacycles

被引:57
作者
Delgado, M [1 ]
Martin, JD [1 ]
机构
[1] CSIC,INST INVEST QUIM,SEVILLE 41092,SPAIN
关键词
D O I
10.1016/S0040-4039(97)01412-3
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A highly efficient and flexible route to trans-fused oxacycles is outlined, which is based on the formation of seven-, eight-, and nine-membered oxacycles by ring-closing metathesis (RCM) as the key step. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码:6299 / 6300
页数:2
相关论文
共 24 条
  • [1] USEFUL DESIGNS IN THE SYNTHESIS OF TRANS-FUSED POLYETHER TOXINS
    ALVAREZ, E
    CANDENAS, ML
    PEREZ, R
    RAVELO, JL
    MARTIN, JD
    [J]. CHEMICAL REVIEWS, 1995, 95 (06) : 1953 - 1980
  • [2] A concise synthesis of ortho-condensed oxane-oxene, oxepene, oxocene and oxonene ring systems
    Alvarez, E
    Delgado, M
    Diaz, MT
    Liu, HX
    Perez, R
    Martin, JD
    [J]. TETRAHEDRON LETTERS, 1996, 37 (16) : 2865 - 2868
  • [3] THE FIRST SYNTHESIS OF THE ABCD RING-SYSTEM OF MANZAMINE-A - CONSTRUCTION OF THE MACROCYCLIC RING-D
    BORER, BC
    DEERENBERG, S
    BIERAUGEL, H
    PANDIT, UK
    [J]. TETRAHEDRON LETTERS, 1994, 35 (19) : 3191 - 3194
  • [4] Clark JS, 1997, TETRAHEDRON LETT, V38, P127
  • [5] Clark JS, 1997, TETRAHEDRON LETT, V38, P123
  • [6] Elliott M. C., 1994, CONTEMP ORG SYNTH, V1, P457
  • [7] Conformationally unbiased macrocyclization reactions by ring closing metathesis
    Furstner, A
    Langemann, K
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (12) : 3942 - 3943
  • [8] Macrocycle formation by ring-closing-metathesis .2. An efficient synthesis of enantiomerically pure (R)-(+)-lasiodiplodin
    Furstner, A
    Kindler, N
    [J]. TETRAHEDRON LETTERS, 1996, 37 (39) : 7005 - 7008
  • [9] RING-CLOSING METATHESIS AND RELATED PROCESSES IN ORGANIC-SYNTHESIS
    GRUBBS, RH
    MILLER, SJ
    FU, GC
    [J]. ACCOUNTS OF CHEMICAL RESEARCH, 1995, 28 (11) : 446 - 452
  • [10] CASCADE CATALYSIS IN SYNTHESIS - AN ENANTIOSELECTIVE ROUTE TO SCH-38516 (AND FLUVIRUCIN-B-1) AGLYCON MACROLACTAM
    HOURI, AF
    XU, ZM
    COGAN, DA
    HOVEYDA, AH
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1995, 117 (10) : 2943 - 2944