Clinical significance of placenta-confined nonmosaic trisomy 16

被引：15

作者：

Brandenburg, H ^{[1
]}

Los, FJ ^{[1
]}

IntVeld, P ^{[1
]}

机构：

[1] UNIV HOSP DIJKZIGT,DEPT CLIN GENET,3015 GD ROTTERDAM,NETHERLANDS

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1996年 / 174卷 / 05期

关键词：

prenatal diagnosis; trisomy; 16; confined placenta abnormality; chorionic villus sampling;

D O I：

10.1016/S0002-9378(96)70631-2

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Since the introduction of chorionic villi sampling in 1984 we have observed five first-trimester cases of nonmosaic placenta confined trisomy 16. At subsequent follow-up it appeared that all five had an adverse maternal or fetal outcome. In three cases the mother had preeclampsia. Two of the infants were born with multiple congenital abnormalities, including tetralogy of Fallot. All children were growth retarded.

引用

页码：1663 / 1664

页数：2