The outcome of intracytoplasmic sperm injection in patients with retrograde ejaculation

被引:25
作者
Nikolettos, N [1 ]
Al-Hasani, S
Baukloh, V
Schöpper, B
Demirel, LC
Baban, N
Sturm, R
Rudolf, K
Tomalak, K
Tinneberg, HR
Diedrich, K
机构
[1] Univ Lubeck, Dept Obstet & Gynecol, D-2400 Lubeck, Germany
[2] Fertil Ctr Hamburg, Hamburg, Germany
[3] Krankenhaus Rosenhohe, Bielefeld, Germany
关键词
ICSI; infertility; retrograde ejaculation;
D O I
10.1093/humrep/14.9.2293
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The objective of this retrospective clinical study was to assess the benefit of assisted fertilization in cases of anejaculatory infertility due to retrograde ejaculation We report the outcome of intracytoplasmic sperm injection (ICSI) treatment. In 16 couples in which the men suffered from retrograde ejaculation. We performed 35 cycles of ICSI with spermatozoa retrieved from post-ejaculatory urine. The patients had been instructed to alkalinize the urine by ingesting sodium bicarbonate before the procedure, The fertilization rate averaged 51.2%. Seven clinical pregnancies were achieved. Three spontaneous first trimester abortions occurred, but three live offspring were delivered and one pregnancy is ongoing. In conclusion, the use of ICSI may be feasible for patients with retrograde ejaculation who are resistant to medical treatment and whose sperm quality is so low or unpredictable that intrauterine insemination or conventional methods of in-vitro fertilization are not possible.
引用
收藏
页码:2293 / 2296
页数:4
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