New β-amino alcohols with a bicyclo[3.3.0]octane scaffold in an asymmetric Henry reaction

被引：64

作者：

Zhong, YW ^{[1
]}

Tian, P ^{[1
]}

Lin, GQ ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China

来源：

TETRAHEDRON-ASYMMETRY | 2004年 / 15卷 / 05期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/j.tetasy.2003.11.040

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A new category of beta-amino alcohols with a bicyclo[3.3.0]octane scaffold has been synthesized and used in the direct asymmetric nitroaldol reaction (Henry reaction). Up to 74% ee was obtained with the addition of nitromethane to relatively bulky aldehydes. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：771 / 776

页数：6

共 49 条

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