Switching Therapies in Multiple Sclerosis

被引：22

作者：

Coyle, Patricia K. ^{[1
]}

机构：

[1] SUNY Stony Brook, Med Ctr, Dept Neurol, Stony Brook, NY 11794 USA

来源：

CNS DRUGS | 2013年 / 27卷 / 04期

关键词：

TECHNOLOGY-ASSESSMENT SUBCOMMITTEE; PLACEBO-CONTROLLED TRIAL; INTERFERON-BETA; GLATIRAMER ACETATE; NEUTRALIZING ANTIBODIES; AMERICAN ACADEMY; DISEASE-ACTIVITY; DOUBLE-BLIND; OPEN-LABEL; NATALIZUMAB;

D O I：

10.1007/s40263-013-0042-5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

There are currently nine approved disease modifying therapies for relapsing forms of multiple sclerosis, with six distinct mechanisms of action. All have side effects, and none are cures. When a patient cannot tolerate therapy, or there is unacceptable breakthrough disease activity, the most common approach is to change drug. No universal guidelines exist for switching therapy. This overview will propose switch principles and suggestions.

引用

页码：239 / 247

页数：9

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