The complex minds of teenagers: Neuroanatomy of personality differs between sexes

被引：65

作者：

Blankstein, Udi ^{[2
]}

Chen, Jerry Y. W. ^{[2
]}

Mincic, Adina M.

McGrath, Patricia A. ^{[4
]}

Davis, Karen D. ^{[1
,2
,3
]}

机构：

[1] Toronto Western Hosp, Toronto Western Res Inst, Univ Hlth Network, Div Brain Imaging & Behav Syst Neurosci, Toronto, ON M5T 2S8, Canada

[2] Univ Toronto, Inst Med Sci, Toronto, ON M5S 1A1, Canada

[3] Univ Toronto, Dept Surg, Toronto, ON, Canada

[4] Hosp Sick Children, Dept Anesthesia & Pain Med, Toronto, ON M5G 1X8, Canada

来源：

NEUROPSYCHOLOGIA | 2009年 / 47卷 / 02期

关键词：

Neuroticism; Extraversion; MRI; VBM; CTA; Sex differences; Adolescents; ANTERIOR CINGULATE CORTEX; BRAIN; DEPRESSION; NEUROTICISM; SYMPTOMS; EXTROVERSION; MOOD; PAIN; FMRI;

D O I：

10.1016/j.neuropsychologia.2008.10.014

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

010107 [宗教学]; 030301 [社会学]; 070906 [古生物学及地层学（含古人类学）];

摘要：

Extraversion and neuroticism influence behaviour and mood. Extreme expressions of these personality traits may predispose individuals to developing chronic functional pains and mood disorders that predominantly affect women. We acquired anatomical MRI scans and personality scores from healthy male and female adolescents and measured gray matter volume (GMV) and cortical thickness to test the hypothesis that neuroticism and extraversion contribute to sex differences in fronto-limbic cortical development during a crucial period of social and biological maturation. In females, extraversion correlated negatively with medial frontal gyrus GMV and neuroticism correlated positively with subgenual anterior cingulate cortex GMV and cortical thickness. Interestingly, correlations between GMV and personality in males showed an opposite effect. Given the association of these cortical areas with social cognition and emotional processing, we suggest that a neuro-maturational divergence during adolescence accounts for the higher prevalence of specific chronic pains and mood disorders in females. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：599 / 603

页数：5

共 27 条

[1]

Meeting of minds: the medial frontal cortex and social cognition [J].

Amodio, DM ;

Frith, CD .

NATURE REVIEWS NEUROSCIENCE, 2006, 7 (04) :268-277

[2]

Puberty and depression: the roles of age, pubertal status and pubertal timing [J].

Angold, A ;

Costello, EJ ;

Worthman, CM .

PSYCHOLOGICAL MEDICINE, 1998, 28 (01) :51-61

[3]

Phobic, panic, and major depressive disorders and the five-factor model of personality [J].

Bienvenu, OJ ;

Nestadt, G ;

Samuels, JF ;

Costa, PT ;

Howard, WT ;

Eaton, WW .

JOURNAL OF NERVOUS AND MENTAL DISEASE, 2001, 189 (03) :154-161

[4]

The social brain in adolescence [J].

Blakemore, Sarah-Jayne .

NATURE REVIEWS NEUROSCIENCE, 2008, 9 (04) :267-277

[5]

Cognitive and emotional influences in anterior cingulate cortex [J].

Bush, G ;

Luu, P ;

Posner, MI .

TRENDS IN COGNITIVE SCIENCES, 2000, 4 (06) :215-222

[6]

An fMRI study of personality influences on brain reactivity to emotional stimuli [J].

Canli, T ;

Zhao, Z ;

Desmond, JE ;

Kang, EJ ;

Gross, J ;

Gabrieli, JDE .

BEHAVIORAL NEUROSCIENCE, 2001, 115 (01) :33-42

[7]

Costa P. T., 1992, Revised NEO Personality (NEO-PI-R) and NEO Five-Factor Inventory (NEO-FFI) manual

[8]

CONTRIBUTIONS OF ANTERIOR CINGULATE CORTEX TO BEHAVIOUR [J].

DEVINSKY, O ;

MORRELL, MJ ;

VOGT, BA .

BRAIN, 1995, 118 :279-306

[9]

The Subgenual Anterior Cingulate Cortex in Mood Disorders [J].

Drevets, Wayne C. ;

Savitz, Jonathan .

CNS SPECTRUMS, 2008, 13 (08) :663-681

[10]

Measuring the thickness of the human cerebral cortex from magnetic resonance images [J].

Fischl, B ;

Dale, AM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (20) :11050-11055

← 1 2 3 →