Synthesis of (E)- and (Z)-5-(bromomethylene)furan-2(5H)-one by bromodecarboxylation of (E)-2-(5-oxofuran-2(5H)-ylidene)acetic acid

被引：15

作者：

Benneche, T

Lönn, J

Scheie, AA

机构：

[1] Univ Oslo, Dept Chem, N-0315 Oslo, Norway

[2] Univ Oslo, Fac Dent, Dept Oral Biol, N-0315 Oslo, Norway

来源：

SYNTHETIC COMMUNICATIONS | 2006年 / 36卷 / 10期

关键词：

alkenes; gamma-alkylidene butenolides; bromodecarboxylation; carboxylic acids; halogenations;

D O I：

10.1080/00397910500522108

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(E)- and (Z)-5-(bromomethylene) furan-2(5H)-one have been prepared starting from the commercially available adduct between furan and maleic anhydride. A bromodecarboxylation reaction is a key step in the synthesis. The reaction gives the ( E)- or ( Z)-5-( bromomethylene) furan- 2( 5H)- one as the major product, dependent on the method used in the bromodecarboxylation.

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收藏

页码：1401 / 1404

页数：4

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