A single-base deletion in the thrombopoietin (TPO) gene causes familial essential thrombocythemia through a mechanism of more efficient translation of TPO mRNA

被引：70

作者：

Ghilardi, N ^{[1
]}

Skoda, RC ^{[1
]}

机构：

[1] Univ Basel, Biozentrum, Basel, Switzerland

来源：

BLOOD | 1999年 / 94卷 / 04期

关键词：

D O I：

10.1182/blood.V94.4.1480.416a37c_1480_1482

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

收藏

页码：1480 / 1482

页数：3

相关论文

共 3 条

[1] Thrombopoietin production is inhibited by a translational mechanism
Ghilardi, N
Wiestner, A
Skoda, RC
[J]. BLOOD, 1998, 92 (11) : 4023 - 4030
[2] Familial essential thrombocythemia associated with one-base deletion in the 5′-untranslated region of the thrombopoietin gene
Kondo, T
Okabe, M
Sanada, M
Kurosawa, M
Suzuki, S
Kobayashi, M
Hosokawa, M
Asaka, M
[J]. BLOOD, 1998, 92 (04) : 1091 - 1096
[3] An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia
Wiestner, A
Schlemper, RJ
van der Maas, APC
Skoda, RC
[J]. NATURE GENETICS, 1998, 18 (01) : 49 - 52