Association between physical activity and brain health in older adults

被引：95

作者：

Benedict, Christian ^{[2
]}

Brooks, Samantha J. ^{[2
]}

Kullberg, Joel ^{[1
]}

Nordenskjold, Richard ^{[1
]}

Burgos, Jonathan ^{[2
]}

Le Greves, Madeleine ^{[2
]}

Kilander, Lena ^{[3
]}

Larsson, Elna-Marie ^{[1
]}

Johansson, Lars ^{[1
]}

Ahlstrom, Hakan ^{[1
]}

Lind, Lars ^{[4
]}

Schioth, Helgi B. ^{[2
]}

机构：

[1] Uppsala Univ, Dept Radiol, Uppsala, Sweden

[2] Uppsala Univ, Dept Neurosci, Uppsala, Sweden

[3] Uppsala Univ, Dept Publ Hlth & Caring Sci Geriatr, Uppsala, Sweden

[4] Uppsala Univ, Dept Med Sci, Uppsala, Sweden

来源：

NEUROBIOLOGY OF AGING | 2013年 / 34卷 / 01期

基金：

瑞典研究理事会;

关键词：

Physical activity; Brain morphometry; Cognitive function; Elderly; GRAY-MATTER VOLUME; ENDOTHELIUM-DEPENDENT VASODILATION; EXERCISE; FITNESS; RISK; AGE; COGNITION; DEMENTIA;

D O I：

10.1016/j.neurobiolaging.2012.04.013

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

In the present cross-sectional study, we examined physical activity (PA) and its possible association with cognitive skills and brain structure in 331 cognitively healthy elderly. Based on the number of self-reported light and hard activities for at least 30 minutes per week, participants were assigned to 4 groups representing different levels of PA. The cognitive skills were assessed by the Mini Mental State Examination score, a verbal fluency task, and the Trail-making test as a measure of visuospatial orientation ability. Participants also underwent a magnetic resonance imaging of the brain. Multiple regression analysis revealed that greater PA was associated with a shorter time to complete the Trail-making test, and higher levels of verbal fluency. Further, the level of self-reported PA was positively correlated with brain volume, white matter, as well as a parietal lobe gray matter volume, situated bilaterally at the precuneus. These present cross-sectional results indicate that PA is a lifestyle factor that is linked to brain structure and function in late life. (C) 2013 Elsevier Inc. All rights reserved.

引用

页码：83 / 90

页数：8

共 33 条

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