Clinical Usefulness of ELISPOT Assay on Pericardial Fluid in a Case of Suspected Tuberculous Pericarditis

被引：24

作者：

Biglino, A. ^{[1
,2
]}

Crivelli, P. ^{[1
]}

Concialdi, E. ^{[1
]}

Bolla, C. ^{[1
]}

Montrucchio, G. ^{[1
]}

机构：

[1] Cardinal Massaia Hosp, Infect & Trop Dis Unit, I-14100 Asti, Italy

[2] Univ Turin, Dep Med & Surg Disciplines, Turin, Italy

来源：

INFECTION | 2008年 / 36卷 / 06期

关键词：

D O I：

10.1007/s15010-008-7402-y

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Rapid and accurate diagnosis of tuberculous pericarditis is often difficult, considering the low specificity of both clinical picture and laboratory tests on pericardial fluid, as well as the low sensitivity of microbiological tests. This report documents the feasibility and clinical usefulness of an Interferon (IFN) - gamma ELISpot - TB assay on pericardial fluid cells in a case of suspected tuberculous pericarditis presenting with tamponade. As large pericardial effusions requiring pericardiocentesis are relatively frequent in tuberculous pericarditis, the physician may consider this particular application of ELISpot-TB as a rapid decision aid for starting the treatment.

引用

页码：601 / 604

页数：4

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