Characterization of Therapeutic Antibodies and Related Products

被引：493

作者：

Beck, Alain ^{[1
]}

Wagner-Rousset, Elsa ^{[1
]}

Ayoub, Daniel ^{[1
]}

Van Dorsselaer, Alain ^{[2
,3
]}

Sanglier-Cianferani, Sarah ^{[2
,3
]}

机构：

[1] CIPF, F-74164 St Julien En Genevois, France

[2] Univ Strasbourg, Lab Spectrometrie Masse BioOrgan LSMBO, IPHC, F-67087 Strasbourg, France

[3] CNRS, UMR7178, F-67037 Strasbourg, France

来源：

ANALYTICAL CHEMISTRY | 2013年 / 85卷 / 02期

关键词：

RECOMBINANT MONOCLONAL-ANTIBODY; ORTHOGONAL ARRAY OPTIMIZATION; IONIZATION MASS-SPECTROMETRY; LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY; HYDROPHILIC INTERACTION CHROMATOGRAPHY; N-LINKED OLIGOSACCHARIDES; HIGH-MANNOSE GLYCANS; HOST-CELL PROTEINS; TOF-MS ANALYSIS; STRUCTURAL-CHARACTERIZATION;

D O I：

10.1021/ac3032355

中图分类号：

O65 [分析化学];

学科分类号：

070302 [分析化学];

摘要：

[No abstract available]

引用

页码：715 / 736

页数：22

共 254 条

[1]

Characterization of a high-affinity human antibody with a disulfide bridge in the third complementarity-determining region of the heavy chain [J].

Almagro, Juan Carlos ;

Raghunathan, Gopalan ;

Beil, Eric ;

Janecki, Dariusz J. ;

Chen, Qiang ;

Dinh, Thai ;

LaCombe, Ann ;

Connor, Judy ;

Ware, Mark ;

Kim, Paul H. ;

Swanson, Ronald V. ;

Fransson, Johan .

JOURNAL OF MOLECULAR RECOGNITION, 2012, 25 (03) :125-135

[2]

On-line characterization of monoclonal antibody variants by liquid chromatography-mass spectrometry operating in a two-dimensional format [J].

Alvarez, Melissa ;

Tremintin, Guillaume ;

Wang, Jennifer ;

Eng, Marian ;

Kao, Yung-Hsiang ;

Jeong, Justin ;

Ling, Victor T. ;

Borisov, Oleg V. .

ANALYTICAL BIOCHEMISTRY, 2011, 419 (01) :17-25

[3]

Specific Racemization of Heavy-Chain Cysteine-220 in the Hinge Region of Immunoglobulin Gamma 1 as a Possible Cause of Degradation during Storage [J].

Amano, Masato ;

Hasegawa, Jun ;

Kobayashi, Naoki ;

Kishi, Naoyuki ;

Nakazawa, Takashi ;

Uchiyama, Susumu ;

Fukui, Kiichi .

ANALYTICAL CHEMISTRY, 2011, 83 (10) :3857-3864

[4]

Characterization of antibody variants during process development The tale of incomplete processing of N-terminal secretion peptide [J].

Ambrogelly, Alexandre ;

Liu, Yan-Hui ;

Li, Hong ;

Mengisen, Selina ;

Yao, Bingyi ;

Xu, Wei ;

Cannon-Carlson, Susan .

MABS, 2012, 4 (06) :701-709

[5]

[Anonymous], 2010, BIOPROCESS INT

[6]

Novel roles for the IgG Fc glycan [J].

Anthony, Robert M. ;

Wermeling, Fredrik ;

Ravetch, Jeffrey V. .

GLYCOBIOLOGY OF THE IMMUNE RESPONSE, 2012, 1253 :170-180

[7]

Arakawa T., 2007, Bioproc Int, V5, P36

[8]

Arakawa T., 2007, Bioprocess Int, V5, P52

[9]

Online enzymatic sequencing of glycans from Trastuzumab by phospholipid-assisted capillary electrophoresis [J].

Archer-Hartmann, Stephanie A. ;

Crihfield, Cassandra L. ;

Holland, Lisa A. .

ELECTROPHORESIS, 2011, 32 (24) :3491-3498

[10]

Arico C., 2013, GLYCOSYLATION ENG BI

← 1 2 3 4 5 6 7 8 9 10 →