Advances in the therapy for sepsis in children

被引：29

作者：

Anderson, MR

Blumer, JL

机构：

[1] RAINBOW BABIES & CHILDRENS HOSP, DIV PEDIAT PHARMACOL & CRIT CARE, DEPT PEDIAT, CLEVELAND, OH 44106 USA

[2] CASE WESTERN RESERVE UNIV, SCH MED, DEPT PEDIAT, DIV PEDIAT CRIT CARE, CLEVELAND, OH 44106 USA

[3] CASE WESTERN RESERVE UNIV, SCH MED, DEPT PHARMACOL, CLEVELAND, OH 44106 USA

来源：

PEDIATRIC CLINICS OF NORTH AMERICA | 1997年 / 44卷 / 01期

关键词：

D O I：

10.1016/S0031-3955(05)70469-7

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Sepsis remains a major clinical problem in children, with a high mortality rate. Recent discoveries have identified the major cytokines involved in sepsis and several anticytokine strategies have been used in clinical trials. Antiendotoxin, anticytokine, and even steroid therapy have been studied in humans, with limited success. Several of the clinical trials of immunotherapy in sepsis are reviewed, and the inherent pitfalls in the varied clinical approaches investigated are analyzed.

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页码：179 / +

页数：1

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