Conservation of the multidrug resistance efflux gene oprM in Pseudomonas aeruginosa

被引：21

作者：

Bianco, N ^{[1
]}

Neshat, S ^{[1
]}

Poole, K ^{[1
]}

机构：

[1] QUEENS UNIV,DEPT MICROBIOL & IMMUNOL,KINGSTON,ON K7L 3N6,CANADA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1997年 / 41卷 / 04期

关键词：

D O I：

10.1128/AAC.41.4.853

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

An intragenic probe derived from the multidrug resistance gene oprM hybridized with genomic DNA from all 20 serotypes of Pseudomonas aeruginosa and from all 34 environmental and clinical isolates tested, indicating that the MexA-MexB-OprM multidrug efflux system is highly conserved in this organism. The oprM probe also hybridized with genomic DNA from Pseudomonas aureofaciens, Pseudomonas chlororaphis, Pseudomonas syringae, Burkholderia pseudomallei, and Pseudomonas putida, suggesting that efflux-mediated multidrug resistance mechanisms may be somewhat broadly distributed.

引用

页码：853 / 856

页数：4

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