Treatment of non-unions with bone defects: Which option and why?

被引：72

作者：

Ashman, O. ^{[1
]}

Phillips, A. M. ^{[1
]}

机构：

[1] Kings Coll Hosp London, London SE5 9RS, England

来源：

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED | 2013年 / 44卷

关键词：

Bone defects; Non-union; Bone shortening; Distraction osteogenesis; Bone grafts; Bone substitutes; Stem cells; Growth factors; Scaffolds; Gene therapy; RECONSTRUCTION; MANAGEMENT;

D O I：

10.1016/S0020-1383(13)70010-X

中图分类号：

R4 [临床医学];

学科分类号：

100218 [急诊医学];

摘要：

Bone defects associated with non-unions occur as a result of the initial insult or as a consequence of bone excision following non-union development. Historically management of this clinical scenario consisted mainly of amputation, which provided a short recovery period but a significant loss of limb function. Today treatment has evolved and multiple options are available for reconstruction of the bone defect. Broadly these are: bone shortening with lengthening later or bone transport and 'docking' (distraction osteogenesis based techniques); the use of vascularised and non-vascularised bone grafts; bone substitutes; stem cells; growth factors; scaffolds and gene therapy. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：S43 / S45

页数：3

共 19 条

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Limb-lengthening, skeletal reconstruction, and bone transport with the Ilizarov method [J].