Functional Imaging in Chronic Migraine

被引：26

作者：

Maniyar, Farooq H. ^{[1
,2
,3
]}

Goadsby, Peter J. ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Neurol, Headache Grp, San Francisco, CA 94115 USA

[2] Royal London Hosp, Whitechapel London E1 1BB, England

[3] Basildon & Thurrock Univ Hosp NHS Fdn Trust, Basildon SS16 5NL, Essex, England

来源：

CURRENT PAIN AND HEADACHE REPORTS | 2013年 / 17卷 / 05期

关键词：

Chronic migraine; Functional; PET; fMRI; Frequency; Peri-aqueductal grey; Dorsal pons; Basal ganglia; Hippocampus; Orbito-frontal cortex; Connectivity; Medication overuse headache; POSITRON EMISSION TOMOGRAPHY; BRAIN-STEM ACTIVATION; VASCULAR MALFORMATION; ORBITOFRONTAL CORTEX; HEADACHE; STRESS; IRON; ADAPTATION; WITHDRAWAL; NUCLEI;

D O I：

10.1007/s11916-013-0333-z

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

Chronic migraine is a relatively common disorder in neurological terms that causes very significant disability at a high cost. The precise mechanisms behind the progression of episodic migraine to chronic migraine are not well understood. Functional neuro-imaging works on the basis that neuronal activations are associated with changes in regional cerebral blood flow, and it can help us answer some of these questions. In this review, we discuss important recent studies in chronic migraine or studies relating to increasing frequency of migraine attacks. The findings show that increasing frequency of migraine attacks is associated with changes in key brainstem areas, basal ganglia and various cortical areas involved in pain.

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