Immunity and retroviral superantigens in humans

被引：12

作者：

Woodland, DL ^{[1
]}

机构：

[1] Trudeau Inst Inc, Saranac Lake, NY 12983 USA

来源：

TRENDS IN IMMUNOLOGY | 2002年 / 23卷 / 02期

关键词：

D O I：

10.1016/S1471-4906(01)02146-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Several studies have suggested that some viruses use superantigens to modulate immune responses in humans. However, the identification and characterization of putative viral superantigens has proven to be very difficult. Two recent papers confirm the presence of an endogenous retroviral superantigen in humans, and show that its expression can be induced by secondary viral infections. The up-regulation of expression of endogenous retroviral superantigens has substantial implications for understanding the pathology of virus infections and human disease.

引用

页码：57 / 58

页数：2

共 17 条

[1]

ACHAORBEA H, 1995, ANNU REV IMMUNOL, V13, P459, DOI 10.1146/annurev.immunol.13.1.459

[2]

Ardavín C, 1999, J IMMUNOL, V162, P2538

[3] IN-VIVO EFFECTS OF SUPERANTIGENS [J].