Comparative evaluation of endodontic irrigant against Enterococcus faecalis biofilms

被引：151

作者：

Dunavant, Thomas R.

Regan, John D.

Glickman, Gerald N.

Solomon, Eric S.

Honeyman, Allen L.

机构：

[1] Texas A&M Univ Syst, Hlth Sci Ctr, Baylor Coll Dent, Dept Biomed Sci, Dallas, TX 75246 USA

[2] Texas A&M Univ Syst, Hlth Sci Ctr, Baylor Coll Dent, Dept Inst Res, Dallas, TX 75246 USA

[3] Texas A&M Univ Syst, Hlth Sci Ctr, Baylor Coll Dent, Dept Endodont, Dallas, TX 75246 USA

来源：

JOURNAL OF ENDODONTICS | 2006年 / 32卷 / 06期

关键词：

biofilm; BioPure MTAD; chlorhexidine; EDTA; endodontic irrigants; SmearClear; sodium hypochlorite;

D O I：

10.1016/j.joen.2005.09.001

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The aim of this study was to compare the efficacy of root canal irrigants against E. faecalis biofilms using a novel in vitro testing system. Biofilms grown in a flow cell system were submerged in test irrigants for either 1 or 5 minutes. Statistical analysis revealed a significant relationship between test agent and percentage kill of the biofilm bacteria (P < 0.05). No statistically significant relationship between time and percentage kill was found. The percentage kill of the biofilm bacteria was: 6% NaOCl (>99.99%), 1% NaOl (99.78%), Smear Clear(TM) (78.06%), 2% chlorhexidine (60.49%), REDTA (26.99%), and BioPure(TM) MTAD(TM) (16.08%). Post-hoc analysis showed a significant difference between 1% and 6% NaOCl, and all other agents including Smear Clear(TM), 2% chlorhexidine, REDTA, and BioPure(TM) MTAD(TM) (P < 0.05). Within the parameters of this study, both 1% NaOCl and 6% NaOCl were more efficient in eliminating E. faecalis biofilm than the other solutions tested.

引用

页码：527 / 531

页数：5

共 35 条

[1] Susceptibilties of two Enterococcus faecalis phenotypes to root canal medications [J].