Extended gastritis cystica profunda associated with Epstein-Barr virus-positive dysplasia and carcinoma with lymphoid stroma

被引：31

作者：

Kim, Lucia ^{[1
]}

Kim, Joon Mee ^{[1
]}

Hur, Yoon Seok ^{[2
]}

Shin, Yong Woon ^{[3
]}

Park, In Suh ^{[1
]}

Choi, Suk Jin ^{[1
]}

Han, Jee Young ^{[1
]}

Chu, Young Chae ^{[1
]}

Kim, Kyu Ho ^{[1
]}

机构：

[1] Inha Univ, Coll Med, Dept Pathol, Inchon 400711, South Korea

[2] Inha Univ, Coll Med, Dept Gen Surg, Inchon 400711, South Korea

[3] Inha Univ, Coll Med, Dept Gastroenterol, Inchon 400711, South Korea

来源：

PATHOLOGY INTERNATIONAL | 2012年 / 62卷 / 05期

关键词：

carcinoma with lymphoid stroma; dysplasia; Epstein-Barr virus; gastritis cystica profunda; INFECTION; POLYPOSA; CANCER; BCL-2; CELLS;

D O I：

10.1111/j.1440-1827.2012.02806.x

中图分类号：

R36 [病理学];

学科分类号：

100103 [病原生物学];

摘要：

We report a case of gastritis cystica porfunda (GCP) associated with gastric carcinoma with lymphoid stroma (CLS). There was dysplastic change in the transitional area between GCP and CLS. Epstein-Barr virus (EBV) in situ hybridization (ISH) revealed positive reaction at the dysplastic area as well as at the CLS area. Immunohistochemical staining disclosed that dysplastic epithelium was similar to GCP in CK 20, MUC5AC, and E-cadherin expression, but similar to CLS in MUC6, CEA, p53, c-erb-B2, and EBV-ISH expression. Results of the EBV-ISH suggested that EBV infection may play a role in dysplastic change.

引用

页码：351 / 355

页数：5

共 26 条

[1]

PATHOLOGICAL FEATURES AND MUCIN HISTOCHEMISTRY OF PRIMARY GASTRIC STUMP CARCINOMA ASSOCIATED WITH GASTRITIS CYSTICA POLYPOSA - A STUDY OF 6 CASES [J].