Brain-Gut Axis: From Basic Understanding to Treatment of IBS and Related Disorders

被引：71

作者：

Camilleri, Michael ^{[1
]}

Di Lorenzo, Carlo ^{[2
]}

机构：

[1] Mayo Clin, Coll Med, Rochester, MN 55905 USA

[2] Nationwide Childrens Hosp, Div Pediat Gastroenterol, Columbus, OH USA

来源：

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION | 2012年 / 54卷 / 04期

基金：

美国国家卫生研究院;

关键词：

immune function; irritable bowel syndrome; motility; pain; secretion; sensation; IRRITABLE-BOWEL-SYNDROME; FUNCTIONAL GASTROINTESTINAL DISORDERS; RECEPTOR ANTAGONIST RAMOSETRON; ACID TRANSPORTER INHIBITOR; ALTERED RECTAL PERCEPTION; PLACEBO-CONTROLLED TRIAL; ONCE-DAILY LINACLOTIDE; DOUBLE-BLIND; ABDOMINAL-PAIN; CLINICAL-TRIAL;

D O I：

10.1097/MPG.0b013e31823d34c3

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

The present review describes advances in understanding the mechanisms and provide an update of present and promising therapy directed at the gut or the brain in the treatment of irritable bowel syndrome (IBS). The diagnosis of IBS typically is based on identification of symptoms, such as the Rome III criteria for IBS in adults and children. The criteria are similar in children and adults. The focus of the present review is the bowel dysfunction associated with IBS.

引用

收藏

页码：446 / 453

页数：8

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