One-pot synthesis of homotryptamines from indoles

被引:18
作者
Denhart, DJ [1 ]
Mattson, RJ [1 ]
Ditta, JL [1 ]
Macor, JE [1 ]
机构
[1] Bristol Myers Squibb Co, Pharmaceut Res Inst, Wallingford, CT 06492 USA
关键词
homotryptamine; indole; serotonin; organic catalysis;
D O I
10.1016/j.tetlet.2004.03.070
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A method is presented for the one-pot synthesis of homotryptamines by the MacMillan reaction of indoles with acrolein followed by reductive amination. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:3803 / 3805
页数:3
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