Simple model for tuberculosis in cattle and badgers

被引:53
作者
Cox, DR [1 ]
Donnelly, CA
Bourne, FJ
Gettinby, G
McInerney, JP
Morrison, WI
Woodroffe, R
机构
[1] Univ Oxford Nuffield Coll, New Rd, Oxford OX1 1NF, England
[2] Dept Environm Food & Rural Affairs, Independent Sci Grp Cattle TB, London SW1 4PQ, England
[3] Univ London Imperial Coll Sci & Technol, Fac Med, Dept Infect Dis Epidemiol, London W2 1PG, England
[4] Univ Strathclyde, Dept Stat & Modelling Sci, Glasgow G1 1XH, Lanark, Scotland
[5] Univ Exeter, Ctr Rural Res, Exeter EX4 6TL, Devon, England
[6] Univ Edinburgh, Royal Dick Sch Vet Studies, Ctr Trop Vet Med, Roslin EH25 9RG, Midlothian, Scotland
[7] Univ Calif Davis, Dept Wildlife Fish & Conservat Biol, Davis, CA 95616 USA
关键词
animal ecology; epidemiology; mathematical model;
D O I
10.1073/pnas.0509003102
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
As an aid to the study of bovine tuberculosis (TB), a simple model has been developed of an epidemic involving two species, cattle and badgers. Each species may infect the other. The proportion of animals affected is assumed relatively small so that the usual nonlinear aspects of epidemic theory are avoided. The model is used to study the long-run and transient effect on cattle of culling badgers and the effect of a period without routine testing for TB, such as occurred during the 2001 epidemic of foot-and-mouth disease in Great Britain. Finally, by examining the changes in cattle TB over the last 15 years, and with some other working assumptions, it is estimated that the net reproduction number of the epidemic is approximate to 1.1. The implications for controlling the disease are discussed.
引用
收藏
页码:17588 / 17593
页数:6
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