Antipneumococcal activity of BMS 284756 compared to those of six other agents

被引：16

作者：

Pankuch, GA

Nagai, K

Davies, TA

Jacobs, MR

Appelbaum, PC

机构：

[1] Milton S Hershey Med Ctr, Dept Pathol, Hershey, PA 17033 USA

[2] Case Western Reserve Univ, Cleveland, OH 44106 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 01期

关键词：

D O I：

10.1128/AAC.46.1.251-254.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Antipneumococcal activity of BMS 284756 was compared to those of six agents by MIC and time-kill methodologies. BMS 284756 had the lowest MICs compared to those of ciprofloxacin, levofloxacin, and moxifloxacin against quinolone-susceptible (less than or equal to0.016 to 0.06 mug/ml) and quinolone-resistant (0.03 to 1 mug/ml) pneumococci. BMS 284756 was bactericidal against 11 of 12 strains at two times the MIC after 24 h.

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页码：251 / 254

页数：4

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