Thrombolytic stroke therapy - Past, present, and future

被引:51
作者
Zivin, JA [1 ]
机构
[1] Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA
关键词
D O I
10.1212/WNL.53.1.14
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Until 1995, treatment of strokes consisted exclusively of efforts to prevent recurrence. Proof that tissue plasminogen activator is useful for acute management is changing the approach to stroke patients. The development process has been difficult and the current treatment recommendations have been controversial. Recent successful clinical trials lend additional credence to these concepts. Future treatment strategies will probably include combinations of thrombolytics and neuroprotectants of various types. However, the need to initiate treatment rapidly after stroke onset is likely to continue.
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页码:14 / 19
页数:6
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