Nuclear Bile Acid Receptor Farnesoid X Receptor Meets Nuclear Factor-κB: New Insights into Hepatic Inflammation

被引：32

作者：

Wagner, Martin ^{[1
]}

Zollner, Gernot ^{[1
]}

Trauner, Michael ^{[1
]}

机构：

[1] Med Univ Graz, Lab Expt & Mol Hepatol, Div Gastroenterol & Hepatol, Dept Internal Med, A-8036 Graz, Austria

来源：

HEPATOLOGY | 2008年 / 48卷 / 05期

关键词：

D O I：

10.1002/hep.22668

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

引用

页码：1383 / 1386

页数：4

共 31 条

[1] IKK-β links inflammation to obesity-induced insulin resistance [J].

Arkan, MC ;

Hevener, AL ;

Greten, FR ;

Maeda, S ;

Li, ZW ;

Long, JM ;

Wynshaw-Boris, A ;

Poli, G ;

Olefsky, J ;

Karin, M .

NATURE MEDICINE, 2005, 11 (02) :191-198

[2] Nuclear factor-κB and liver carcinogenesis [J].

Arsura, M ;

Cavin, LG .

CANCER LETTERS, 2005, 229 (02) :157-169

[3] Pharmacological IKK2 inhibition blocks liver steatosis and initiation of non-alcoholic steatohepatitis [J].

Beraza, N. ;

Malato, Y. ;

Borght, S. Vander ;

Liedtke, C. ;

Wasmuth, H. E. ;

Dreano, M. ;

de Vos, R. ;

Roskams, T. ;

Trautwein, C. .

GUT, 2008, 57 (05) :655-663

[4] Hepatocyte-specific IKKγ/NEMO expression determines the degree of liver injury [J].

Beraza, Naiara ;

Ludde, Tom ;

Assmus, Ulrike ;

Roskams, Tania ;

Borght, Sara Vander ;

Trautwein, Christian .

GASTROENTEROLOGY, 2007, 132 (07) :2504-2517

[5] Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB [J].

Cai, DS ;

Yuan, MS ;

Frantz, DF ;

Melendez, PA ;

Hansen, L ;

Lee, J ;

Shoelson, SE .

NATURE MEDICINE, 2005, 11 (02) :183-190

[6] DIFFERENTIAL-EFFECTS OF CHENODEOXYCHOLIC AND URSODEOXYCHOLIC ACIDS ON INTERLEUKIN-1, INTERLEUKIN-6 AND TUMOR-NECROSIS-FACTOR-ALPHA PRODUCTION BY MONOCYTES [J].

CALMUS, Y ;

GUECHOT, J ;

PODEVIN, P ;

BONNEFIS, MT ;

GIBOUDEAU, J ;

POUPON, R .

HEPATOLOGY, 1992, 16 (03) :719-723

[7] Expression of the bile acid receptor FXR in Barrett's esophagus and enhancement of apoptosis by guggulsterone in vitro [J].

De Gottardi, Andrea ;

Dumonceau, Jean-Marc ;

Bruttin, Fabien ;

Vonlaufen, Alain ;

Morard, Isabelle ;

Spahr, Laurent ;

Rubbia-Brandt, Laure ;

Frossard, Jean-Louis ;

Dinjens, Winand N. M. ;

Rabinovitch, Peter S. ;

Hadengue, Antoine .

MOLECULAR CANCER, 2006, 5 (1)

[8]

Diehl Anna Mae, 2004, Clin Liver Dis, V8, P619, DOI 10.1016/j.cld.2004.04.012

[9] Nuclear factor-κB and the hepatic inflammation-fibrosis-cancer axis [J].

Elsharkawy, Ahmed M. ;

Mann, Derek A. .

HEPATOLOGY, 2007, 46 (02) :590-597

[10] Inhibitory effect of NF-κB on 1,25-dihydroxyvitamin D3 and retinoid X receptor function [J].

Farmer, PK ;

He, XF ;

Schmitz, ML ;

Rubin, J ;

Nanes, MS .

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2000, 279 (01) :E213-E220

← 1 2 3 4 →