Capillary electrophoresis separation and permanganate chemiluminescence on-line detection of some alkaloids with β-cyclodextrin as an additive

被引：44

作者：

Gong, ZL ^{[1
]}

Zhang, Y ^{[1
]}

Zhang, H ^{[1
]}

Cheng, JK ^{[1
]}

机构：

[1] Wuhan Univ, Dept Chem, Res Ctr Analyt Sci, Wuhan 430072, Peoples R China

来源：

JOURNAL OF CHROMATOGRAPHY A | 1999年 / 855卷 / 01期

基金：

中国国家自然科学基金; 中国博士后科学基金;

关键词：

chemiluminescence detection; capillary electrophoresis; alkaloids; permanganate;

D O I：

10.1016/S0021-9673(99)00659-7

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Capillary electrophoresis has been used in combination with on-line permanganate chemiluminescence detection for the simultaneous determination of morphine, 6-monoacetylmorphine and heroin. It was found that beta-cyclodextrins could improve the separation efficiency and enhance the chemiluminescence signal. Improved sensitivity over capillary electrophoresis with UV detection was obtained. The procedure has detection limits of 23, 66 and 115 fmol for morphine, 6-monoacetylmorphine and heroin, respectively. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：329 / 335

页数：7

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