Synthesis of aminomethyl substituted silacyclohexanes from divinylsilanes:: An unusually selective hydroformylation aldol condensation sequence

被引：13

作者：

Bärfacker, L ^{[1
]}

El Tom, D ^{[1
]}

Eilbracht, P ^{[1
]}

机构：

[1] Univ Dortmund, Fachbereich Chem, D-44221 Dortmund, Germany

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 21期

关键词：

aldol reactions; amines; carbonylation; hydroformylation; silicon heterocycles; rhodium catalysis;

D O I：

10.1016/S0040-4039(99)00678-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The preparation of aminomethyl substituted silacyclohexane derivatives starting from divinylsilanes and secondary amines is achieved in a selective one-pot tandem hydroformylation / condensation sequence starling with a double olefin carbonylation and proceeding with an enamine generation followed by an aldol condensation step. Final hydrogenation leads to the silacycle in medium up to quantitative yields. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：4031 / 4034

页数：4

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