Molecular evolution of human influenza A/H3N2 virus in Asia and Europe from 2001 to 2003

被引：29

作者：

Chi, XS ^{[1
]}

Bolar, TV ^{[1
]}

Zhao, P ^{[1
]}

Tam, JS ^{[1
]}

Rappaport, R ^{[1
]}

Cheng, SM ^{[1
]}

机构：

[1] Wyeth Vaccines Res, Appl Immunol & Microbiol Div, Pearl River, NY 10965 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2005年 / 43卷 / 12期

关键词：

D O I：

10.1128/JCM.43.12.6130-6132.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Hemagglutinin sequences of 146 human influenza A/H3N2 strains identified in respiratory specimens from Asia and Europe during the 2001-2003 influenza seasons were analyzed by DNA sequencing. Our results suggest that four amino acid substitutions, L251, H75Q, H155T, and Q156H, led to the antigenic conversion of the previously predominant A/Panama/2007/99-like strains to the more recent A/Fujian/411/2002-like strains.

引用

页码：6130 / 6132

页数：3

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