A case of metastatic extra-adrenal pheochromocytoma 12 years after surgery

被引:12
作者
Mori, S
Okura, T [1 ]
Kitami, Y
Takata, Y
Nakamura, M
Watanabe, S
Iwata, T
Hiwada, K
机构
[1] Ehime Univ, Sch Med, Dept Internal Med 2, Matsuyama, Ehime 7910295, Japan
[2] Yawatahama City Gen Hosp, Dept Internal Med, Yawatahama, Ehime, Japan
关键词
metastasis; glucagon test; I-131-metaiodobenzylguanidine scintigraphy (MIBG); long-term follow up;
D O I
10.1291/hypres.25.141
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
At the age of 53, a 65-year-old man had been diagnosed with extra-adrenal pheochromocytoma in the retroperitoneum and underwent total tumorectomy. Afterward, he had his serum catecholamine periodically measured in an outpatient clinic. In February 1999, 12 years after surgery, he complained of lower left abdominal pain. Computed tomography and magnetic resonance imaging revealed an osteolytic lesion in thoracic vertebrae 11Th (Th 11). Although his basal serum and urine catecholamines were at normal levels, glucagon injection increased blood pressure and plasma catecholamine levels. I-131-metaiodobenzyiguanidine (MIBG) scintigraphy was specifically taken up to Th 11. By bone biopsy, the osteolytic lesion in Th 11 was finally diagnosed with metastasis of pheochromocytoma. For post-operative pheochromocytoma, long-term follow-up involving biochemical tests, including serum catecholamines, and MIBG is needed.
引用
收藏
页码:141 / 144
页数:4
相关论文
共 19 条
[1]   Neuron-specific enolase and chromogranin A as markers of neuroendocrine tumours [J].
Baudin, E ;
Gigliotti, A ;
Ducreux, R ;
Ropers, J ;
Comoy, E ;
Sabourin, JC ;
Bidart, JM ;
Cailleux, AF ;
Bonacci, R ;
Ruffié, P ;
Schlumberger, M .
BRITISH JOURNAL OF CANCER, 1998, 78 (08) :1102-1107
[2]   Frequency of pheochromocytoma in adrenal incidentalomas and utility of the glucagon test for the diagnosis [J].
Bernini, GP ;
Vivaldi, MS ;
Argenio, GF ;
Moretti, A ;
Sgro, M ;
Salvetti, A .
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 1997, 20 (02) :65-71
[3]   Pheochromocytoma, a rare cause of hypertension: Long-term follow-up of 55 surgically treated patients [J].
Favia, G ;
Lumachi, F ;
Polistina, F ;
D'Amico, DF .
WORLD JOURNAL OF SURGERY, 1998, 22 (07) :689-694
[4]   Diagnosis of pheochromocytoma using [123I]-compared with [131I]-metaiodobenzylguanidine scintigraphy [J].
Furuta, N ;
Kiyota, H ;
Yoshigoe, F ;
Hasegawa, N ;
Ohishi, Y .
INTERNATIONAL JOURNAL OF UROLOGY, 1999, 6 (03) :119-124
[5]   GLUCAGON AND CLONIDINE TESTING IN THE DIAGNOSIS OF PHEOCHROMOCYTOMA [J].
GROSSMAN, E ;
GOLDSTEIN, DS ;
HOFFMAN, A ;
KEISER, HR .
HYPERTENSION, 1991, 17 (06) :733-741
[6]  
GROUZMANN E, 1989, J CLIN ENDOCR METAB, V64, P808
[7]   Guidelines for hypertension in the elderly - 1999 revised version [J].
Hiwada, K ;
Ogihara, T ;
Matsumoto, M ;
Matsuoka, H ;
Takishita, S ;
Shimamoto, K ;
Toba, K ;
Abe, I ;
Kohara, K ;
Morimoto, S ;
Mikami, H ;
Iwai, K ;
Takasaki, M ;
Kawano, Y ;
Higashiura, K ;
Kozaki, K ;
Eto, M ;
Fujishima, M .
HYPERTENSION RESEARCH-CLINICAL AND EXPERIMENTAL, 1999, 22 (04) :231-259
[8]   The treatment of malignant metaiodobenzylguanidine (131I-MIBG):: A comprehensive review of 116 reported patients [J].
Loh, KC ;
Fitzgerald, PA ;
Matthay, KK ;
Yeo, PPB ;
Price, DC .
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 1997, 20 (11) :648-658
[9]   Pheochromocytoma in Italy: a multicentric retrospective study [J].
Mannelli, M ;
Ianni, L ;
Cilotti, A ;
Conti, A .
EUROPEAN JOURNAL OF ENDOCRINOLOGY, 1999, 141 (06) :619-624
[10]   PHEOCHROMOCYTOMAS IN 72 PATIENTS - CLINICAL AND DIAGNOSTIC FEATURES, TREATMENT AND LONG-TERM RESULTS [J].
MODLIN, IM ;
FARNDON, JR ;
SHEPHERD, A ;
JOHNSTON, IDA ;
KENNEDY, TL ;
MONTGOMERY, DAD ;
WELBOURN, RB .
BRITISH JOURNAL OF SURGERY, 1979, 66 (07) :456-465