Life on the road

被引：9

作者：

Flanagan, JG ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Program Neurosci, Boston, MA 02115 USA

来源：

NATURE | 1999年 / 401卷 / 6755期

关键词：

D O I：

10.1038/44471

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

To form the connections of the nervous system, axons must connect up with the areas that will be their final target. Intermediate targets are thought to act as signposts along the way, sending out guidance molecules that tell the axons which way to go. But a new study shows that these intermediate targets do much more than this, and that they are required to keep the migrating neurons alive.

引用

页码：747 / 748

页数：2

共 5 条

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[3] Neuronal cell death [J].

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[4] The middle and the end: Slit brings guidance and branching together in axon pathway selection [J].

Van Vactor, D ;

Flanagan, JG .

NEURON, 1999, 22 (04) :649-652

[5] En passant neurotrophic action of an intermediate axonal target in the developing mammalian CNS [J].

Wang, H ;

Tessier-Lavigne, M .

NATURE, 1999, 401 (6755) :765-769

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