Nonthyroidal illness syndrome: evaluation of thyroid function in sick patients

被引:33
作者
Langton, JE
Brent, GA
机构
[1] VA Greater Los Angeles Healthcare Syst, Dept Med, Div Endocrinol, Los Angeles, CA USA
[2] Univ Calif Los Angeles, Sch Med, Los Angeles, CA USA
关键词
D O I
10.1016/S0889-8529(01)00008-1
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Changes in thyroid function in the setting of systemic illness, surgery, or fasting are referred to as nonthyroidal illness syndrome (also called "sick euthyroid syndrome"). Nonthyroidal illness influences thyroid hormone production and action at multiple levels including the hypothalamic-pituitary-thyroid axis, thyroid hormone transport, and metabolism. This article reviews the pathophysiology of these changes and the influence on interpretation of thyroid function tests. Guidelines are provided for the assessment of thyroid function in sick patients and the options for treatment.
引用
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页码:159 / +
页数:15
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