Synthesis of C-13 enriched sialyllactones and their characterization using isotope edited inverse detected NMR spectroscopy

C-13 enriched monosaccharide based sialyllactones were prepared in order to perform isotope edited NMR experiments for their characterization. In the inverse detected experiments only those protons long range coupled to the enriched nuclei are detected, providing a potentially powerful tool for studying in vitro sialyllactone formation. (C) 1997 Elsevier Science Ltd.