Invasive meningococcal disease among university undergraduates: association with universities providing relatively large amounts of catered hall accommodation

被引:44
作者
Neal, KR [1 ]
Nguyen-Van-Tam, J
Monk, P
O'Brien, SJ
Stuart, J
Ramsay, M
机构
[1] Univ Nottingham, Dept Publ Hlth Med & Epidemiol, Nottingham NG7 2UH, England
[2] Dept Publ Hlth, Leicester LE5 4QF, Leics, England
[3] Ruchill Hosp, Scottish Ctr Infect & Environm Hlth, Glasgow G20 9NB, Lanark, Scotland
[4] Gloucestershire Royal Infirm, CDSC S&W, Gloucester GL1 3NN, England
[5] CDSC, Immunisat Div, London NW9 5EQ, England
关键词
D O I
10.1017/S0950268899002368
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The incidence of invasive meningococcal disease (IMD) among UK university students and non-students of similar age was investigated. In addition, we sought to identify structural risk factors associated with high rates of IMD in individual universities. Cases were ascertained via Consultants in Communicable Disease Control (or equivalent officers) between September 1994 and March 1997. Data on individual universities were obtained from university accommodation officers. University students had an increased annual rate of invasive meningococcal disease (13.2/10(5), 95 % CI 11.2-15.2) compared with non-students of similar age in the same health districts (5/5/10(5), CI 4.7-6.4) and in those health districts without universities (3.7/10(5), CI 2.9-4.4). This trend was highly significant. Regression analysis demonstrated catered hall accommodation to be the main structural risk factor. Higher rates of disease were observed at universities providing catered hall places for > 10% of their student population (15.3/10(5), CI 11.8-18.8) compared with those providing places for < 10% of students (5.9/10(5), CI 4.1-7.7). The majority of IMD amongst students was caused by serogroup B organisms. University students in the UK are at increased risk of IMD compared with non-students of a similar age. The incidence of IMD tends to be greatest at universities with a high provision of catered hall accommodation.
引用
收藏
页码:351 / 357
页数:7
相关论文
共 13 条
[1]  
[Anonymous], 1996, IMMUNISATION INFECT
[2]   EARLY TREATMENT OF MENINGOCOCCAL DISEASE [J].
CARTWRIGHT, K ;
STRANG, J ;
GOSSAIN, S ;
BEGG, N .
BRITISH MEDICAL JOURNAL, 1992, 305 (6856) :774-774
[3]   Serogroup B meningococcal disease in the Norwegian aimed forces - What can we learn from an inconclusive vaccine protection trial? [J].
Djupesland, PG ;
Bjune, G ;
Hoiby, EA ;
Gronnesby, JK ;
Mundal, R .
EUROPEAN JOURNAL OF PUBLIC HEALTH, 1997, 7 (03) :261-266
[4]  
Gardner M, 1992, STAT CONFIDENCE CONF, P28
[5]  
GLOVER JA, 1920, SPECIAL REPORT SERIE, V50, P133
[6]  
Hubert B, 1997, Euro Surveill, V2, P69
[7]   SHOULD COLLEGE-STUDENTS BE VACCINATED AGAINST MENINGOCOCCAL DISEASE - A COST-BENEFIT-ANALYSIS [J].
JACKSON, LA ;
SCHUCHAT, A ;
GORSKY, RD ;
WENGER, JD .
AMERICAN JOURNAL OF PUBLIC HEALTH, 1995, 85 (06) :843-845
[8]  
Jones D., 1995, MENINGOCOCCAL DIS, P147
[9]  
Ramsay M, 1997, Commun Dis Rep CDR Rev, V7, pR49
[10]  
Stuart J M, 1997, Commun Dis Rep CDR Rev, V7, pR3