Growth factors in angiogenesis: Current interest and therapeutic potential

被引：68

作者：

ColvilleNash, PR

Willoughby, DA

机构：

[1] UNIV LONDON ST BARTHOLOMEWS HOSP MED COLL,DEPT EXPT PATHOL,LONDON EC1M 6BQ,ENGLAND

[2] ROYAL LONDON HOSP,SCH MED & DENT,LONDON EC1M 6BQ,ENGLAND

来源：

MOLECULAR MEDICINE TODAY | 1997年 / 3卷 / 01期

关键词：

D O I：

10.1016/S1357-4310(96)10048-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Angiogenesis, the process of new blood vessel development, is an essential component of the body's physiology and contributes to the pathogenesis of a variety of diseases such as benign and malignant neoplasia and rheumatoid arthritis. Failure of this physiological response is also important in abnormalities of wound healing in diseases such as duodenal ulceration and diabetes. Angiogenesis is controlled by a variety of factors that initiate, control and terminate this complex, multi-stage process. This review covers those factors that are exciting much interest currently and have potential for incorporation into clinical medicine.

引用

页码：14 / 23

页数：10

共 59 条

[1] ISOLATION AND CULTURE OF SYNOVIAL MICROVASCULAR ENDOTHELIAL-CELLS - CHARACTERIZATION AND ASSESSMENT OF ADHESION MOLECULE EXPRESSION [J].