Flavones and sesquiterpene lactones from Achillea atrata subsp multifida:: Antimicrobial activity

被引：85

作者：

Aljancic, I

Vajs, V

Menkovic, N

Karadzic, I

Juranic, N

Milosavljevic, S

Macura, S ^{[1
]}

机构：

[1] Mayo Clin & Mayo Fdn, Mayo Grad Sch, Dept Biochem, Rochester, MN 55905 USA

[2] Inst Chem Technol & Met, YU-11000 Belgrade, Yugoslavia

[3] Inst Med Plant Res, YU-11000 Belgrade, Yugoslavia

[4] Sch Med, Dept Chem, YU-11000 Belgrade, Yugoslavia

[5] Univ Belgrade, Fac Chem, YU-11001 Belgrade, Yugoslavia

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 06期

关键词：

D O I：

10.1021/np980536m

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four flavones (1-4) and nine sesquiterpene lactones (5-13), one of them (5) a new compound, were isolated from the aerial parts of Achillea atrata L. subsp. multifida. Although the crude extract demonstrated in vitro inhibitory activity against Candida albicans and Bacillus subtilis, all isolated flavones were active against B. subtilis. Flavones 1, 2, and 3 were also active against C. albicans, while 1 and 3 exhibited activity against E. coli, as well. None of the tested lactones (7, 9, 12, and 13) showed any antimicrobial activity.

引用

页码：909 / 911

页数：3

共 20 条

[1] TOTAL SYNTHESES OF (+)-TEMISIN, (+)-MELITENSIN AND RELATED ELEMANOLIDES FROM (-)-ARTEMISIN [J].