Sarcopenia: revised European consensus on definition and diagnosis

被引:10432
作者
Cruz-Jentoft, Alfonso J. [1 ]
Bahat, Gulistan [2 ]
Bauer, Juergen [3 ]
Boirie, Yves [4 ]
Bruyere, Olivier [5 ]
Cederholm, Tommy [6 ,7 ]
Cooper, Cyrus [8 ,9 ]
Landi, Francesco [10 ]
Rolland, Yves [11 ]
Sayer, Avan Aihie [12 ,13 ]
Schneider, Stephane M. [14 ]
Sieber, Cornel C. [15 ]
Topinkova, Eva [16 ,17 ]
Vandewoude, Maurits [18 ]
Visser, Marjolein [19 ,20 ]
Zamboni, Mauro [21 ]
机构
[1] Hosp Univ Ramon y Cajal IRYCIS, Serv Geriatr, Madrid, Spain
[2] Istanbul Univ, Istanbul Med Sch, Div Geriatr, Dept Internal Med, Istanbul, Turkey
[3] Heidelberg Univ, Ctr Geriatr Med, Agaples Bethanien Krankenhaus, Heidelberg, Germany
[4] CHU Clermont Ferrand, Res Dept, Clermont Ferrand, France
[5] Univ Liege, Dept Publ Hlth Epidemiol & Hlth Econ, Liege, Belgium
[6] Uppsala Univ, Dept Publ Hlth & Caring Sci, Clin Nutr & Metab, Uppsala, Sweden
[7] Karolinska Univ Hosp, Theme Ageing, Stockholm, Sweden
[8] Univ Southampton, MRC Lifecourse Epidemiol Unit, Southampton, Hants, England
[9] Univ Oxford, Dept Epidemiol, Ox, England
[10] Univ Cattolica Sacro Cuore, Inst Med Interna & Geriatria, Rome, Italy
[11] Hosp & Univ Toulouse, Dept Geriatr, Toulouse, France
[12] Newcastle Upon Tyne Hosp NHS Fdn Trust, NIHR Newcastle Biomed Res Ctr, Newcastle, England
[13] Newcastle Univ, Fac Med Sci, Newcastle, England
[14] Univ Cote Azur, CHU Nice, Dept Gastroenterol & Clin Nutr, Nice, France
[15] Friedrich Alexander Univ, Inst Biomed & Ageing, Dept Internal Med Geriatr, Erlangen, Germany
[16] Charles Univ Prague, Fac Med 1, Dept Geriatr, Prague, Czech Republic
[17] Gen Fac Hosp, Prague, Czech Republic
[18] Univ Antwerp, Dept Geriatr, Ziekenhuisnetwerk Antwerpen ZNA, Antwerp, Belgium
[19] Vrije Univ Amsterdam, Fac Sci, Dept Hlth Sci, Amsterdam, Netherlands
[20] Amsterdam Publ Hlth Res Inst, Amsterdam, Netherlands
[21] Univ Verona, Geriatr Sect, Dept Med, Verona, Italy
关键词
sarcopenia; muscle strength; physical performance; muscle assessment; EWGSOP2; older people; SKELETAL-MUSCLE MASS; BIOELECTRICAL-IMPEDANCE ANALYSIS; OF-LIFE QUESTIONNAIRE; LOWER-EXTREMITY FUNCTION; ADIPOSE-TISSUE VOLUMES; DWELLING OLDER-PEOPLE; ALL-CAUSE MORTALITY; COMPUTED-TOMOGRAPHY; GRIP STRENGTH; GAIT SPEED;
D O I
10.1093/ageing/afy169
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
030301 [社会学]; 100201 [内科学];
摘要
Background in 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings. Objectives to increase consistency of research design, clinical diagnoses and ultimately, care for people with sarcopenia. Recommendations sarcopenia is a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age but can also occur earlier in life. In this updated consensus paper on sarcopenia, EWGSOP2: (1) focuses on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarcopenia diagnosis, and identifies poor physical performance as indicative of severe sarcopenia; (2) updates the clinical algorithm that can be used for sarcopenia case-finding, diagnosis and confirmation, and severity determination and (3) provides clear cut-off points for measurements of variables that identify and characterise sarcopenia. Conclusions EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat patients at risk for sarcopenia to take actions that will promote early detection and treatment. We also encourage more research in the field of sarcopenia in order to prevent or delay adverse health outcomes that incur a heavy burden for patients and healthcare systems.
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页码:16 / 31
页数:16
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