Herpesvirus interference with virus-specific antibodies: Bridging antibodies, internalizing antibodies, and hiding from antibodies

被引：15

作者：

Favoreel, HW

Van Minnebruggen, G

Van de Walle, GR

Ficinska, J

Nauwynck, HJ

机构：

[1] Univ Ghent, Fac Vet Med, Virol Lab, B-9820 Merelbeke, Belgium

[2] Univ Ghent, Fac Vet Med, Immunol Lab, B-9820 Merelbeke, Belgium

来源：

VETERINARY MICROBIOLOGY | 2006年 / 113卷 / 3-4期

关键词：

alphaherpesvirus; humoral immunity; antibodies; immune invasion;

D O I：

10.1016/j.vetmic.2005.11.003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Herpesviruses have developed different tools to thwart efficient antibody-dependent neutralisation and lysis of virions and elimination of infected cells. This overview will briefly summarize different of these tools, including (i) viral Fc receptors and the resulting process of antibody bridging, (ii) internalization of individual viral proteins and clustered antibody-antigen complexes from the plasma membrane of infected cells, and (iii) directed egress of virus particles to sites of intimate cell-cell contact that are difficult to access for antibodies. (c) 2005 Elsevier B.V. All rights reserved.

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收藏

页码：257 / 263

页数：7

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