Total synthesis of bafilomycin A(1) .2. The assemblage and completion of the synthesis.

被引：52

作者：

Toshima, K

Yamaguchi, H

Jyojima, T

Noguchi, Y

Nakata, M

Matsumura, S

机构：

[1] Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Yokohama 223, 3-14-1 Hiyoshi, Kohoku-ku

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 07期

关键词：

D O I：

10.1016/0040-4039(95)02351-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of the macrolide antibiotic, bafilomycin A(1) (1), has been achieved by a convergent route involving aldol condensation between the 16-membered lactonic aldehyde 2 and the ethyl ketone 3, followed by desilylation.

引用

页码：1073 / 1076

页数：4

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