Conservation of Brachyury, Mef2, and Snail in the myogenic lineage of jellyfish:: A connection to the mesoderm of bilateria

被引:103
作者
Spring, J [1 ]
Yanze, N [1 ]
Jösch, C [1 ]
Middel, AM [1 ]
Winninger, B [1 ]
Schmid, V [1 ]
机构
[1] Univ Basel, Inst Zool, Bioctr Pharmactr, CH-4056 Basel, Switzerland
关键词
cnidaria; mesoderm; evolution; myogenesis; regulatory genes;
D O I
10.1006/dbio.2002.0616
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
One major difference between simple metazoans such as cnidarians and all the bilaterian animals is thought to involve the invention of mesoderm. The terms diploblasts and triploblasts are therefore, often used to group prebilaterian and bilaterian animals, respectively. However, jellyfish contain well developed striated and smooth muscle tissues that derive from the entocodon, a mesoderm-like tissue formed during medusa development. We investigated the hypothesis, that the entocodon could be homologous to the third germ layer of bilaterians by analyzing the structures and expression patterns of the homologues of Brachyury, Mef2, and Snail in the jellyfish Podocoryne carnea. These are regulatory genes from the T-box, MADS-box and zinc finger families known to play important roles in bilaterian mesoderm patterning and muscle differentiation. The sequence and expression data demonstrate that the genes are structurally and functionally conserved and even more similar to humans or other deuterostomes than to protostome model organisms such as Drosophila or Caenorhabditis elegans. Based on these data we conclude that the common ancestor of the cnidarians and bilaterians not only shared genes that play a role in regulating myogenesis but already used them to develop and differentiate muscle systems similar to those of triploblasts. (C) 2002 Elsevier Science (USA).
引用
收藏
页码:372 / 384
页数:13
相关论文
共 59 条
  • [1] LIFE STAGE AND TISSUE-SPECIFIC EXPRESSION OF THE HOMEOBOX GENE CNOX1-PC OF THE HYDROZOAN PODOCORYNE CARNEA
    AERNE, BL
    BAADER, CD
    SCHMID, V
    [J]. DEVELOPMENTAL BIOLOGY, 1995, 169 (02) : 547 - 556
  • [2] Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
    Altschul, SF
    Madden, TL
    Schaffer, AA
    Zhang, JH
    Zhang, Z
    Miller, W
    Lipman, DJ
    [J]. NUCLEIC ACIDS RESEARCH, 1997, 25 (17) : 3389 - 3402
  • [3] Brachyury (T) expression in embryos of a Larvacean Urochordate, Oikopleura dioica, and the ancestral role of T
    Bassham, S
    Postlethwait, J
    [J]. DEVELOPMENTAL BIOLOGY, 2000, 220 (02) : 322 - 332
  • [4] twist: A myogenic switch in Drosophila
    Baylies, MK
    Bate, M
    [J]. SCIENCE, 1996, 272 (5267) : 1481 - 1484
  • [5] Invertebrate myogenesis: looking back to the future of muscle development
    Baylies, MK
    Michelson, AM
    [J]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 2001, 11 (04) : 431 - 439
  • [6] Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins
    Black, BL
    Olson, EN
    [J]. ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, 1998, 14 : 167 - 196
  • [7] ELECTRON-MICROSCOPIC STUDY OF EARLY DEVELOPMENTAL STAGES, MYOGENESIS, OOGENESIS AND CNIDOGENESIS IN ANTHOMEDUSA, PODOCORYNE-CARNEA-M SARS
    BOELSTERLI, U
    [J]. JOURNAL OF MORPHOLOGY, 1977, 154 (02) : 259 - 289
  • [8] Boero F., 1987, P229
  • [9] The cnidarian premises of metazoan evolution: from triploblasty, to coelom formation, to metamery
    Boero, F
    Gravili, C
    Pagliara, P
    Piraino, S
    Bouillon, J
    Schmid, V
    [J]. ITALIAN JOURNAL OF ZOOLOGY, 1998, 65 (01) : 5 - 9
  • [10] Bouillon J., 1995, TRAITE ZOOL, P29, DOI DOI 10.1007/B97636