Dorisenones, cytotoxic spongian diterpenoids, from the nudibranch Chromodoris obsoleta

被引：44

作者：

Miyamoto, T

Sakamoto, K

Arao, K

Komori, T

Higuchi, R

Sasaki, T

机构：

[1] KYUSHU UNIV, FAC PHARMACEUT SCI, HIGASHI KU, FUKUOKA 81282, JAPAN

[2] KANAZAWA UNIV, CANC RES INST, KANAZAWA, ISHIKAWA 920, JAPAN

来源：

TETRAHEDRON | 1996年 / 52卷 / 24期

关键词：

D O I：

10.1016/0040-4020(96)00388-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Seven new cytotoxic spongian diterpenoids, dorisenones A (1), B (2), C (3), D (4), 7 alpha-hydroxyspongian-16-one (5), 15 alpha, 16 alpha-diacetoxy-11, 12 beta-epoxyspongian (6) and 7 alpha-acetoxydendrillol-3 (7) were isolated from a Japanese marine mollusk Chromodoris obsoleta (Chromodorididae), together with four known spongian diterpenoids. Their structures have been elucidated by spectroscopic evidence and single crystal X-ray analysis. Copyright (C) 1996 Elsevier Science Ltd

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页码：8187 / 8198

页数：12

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