Lymphoid organs contain diverse cells expressing self-molecules

被引：13

作者：

Pugliese, A ^{[1
]}

Diez, J ^{[1
]}

机构：

[1] Univ Miami, Sch Med, Diabet Res Inst, Immunogenet Program, Miami, FL 33136 USA

来源：

NATURE IMMUNOLOGY | 2002年 / 3卷 / 04期

关键词：

D O I：

10.1038/ni0402-335b

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：335 / 336

页数：2

共 8 条

[1]

Derbinski J, 2001, NAT IMMUNOL, V2, P1032, DOI 10.1038/ni723

[2] Differential splicing of the IA-2 mRNA in pancreas and lymphoid organs as a permissive genetic mechanism for autoimmunity against the IA-2 type 1 diabetes autoantigen [J].

Diez, J ;

Park, Y ;

Zeller, M ;

Brown, D ;

Garza, D ;

Ricordi, C ;

Hutton, J ;

Eisenbarth, GS ;

Pugliese, A .

DIABETES, 2001, 50 (04) :895-900

[3] Peripheral-antigen-expressing cells in thymic medulla: factors in self-tolerance and autoimmunity [J].

Hanahan, D .

CURRENT OPINION IN IMMUNOLOGY, 1998, 10 (06) :656-662

[4] Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla [J].

Heino, M ;

Peterson, P ;

Kudoh, J ;

Nagamine, K ;

Lagerstedt, A ;

Ovod, V ;

Ranki, A ;

Rantala, I ;

Nieminen, M ;

Tuukkanen, J ;

Scott, HS ;

Antonarakis, SE ;

Shimizu, N ;

Krohn, K .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1999, 257 (03) :821-825

[5] Self-antigen-presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organs [J].

Pugliese, A ;

Brown, D ;

Garza, D ;

Murchison, D ;

Zeller, M ;

Redondo, M ;

Diez, J ;

Eisenbarth, GS ;

Patel, DD ;

Ricordi, C .

JOURNAL OF CLINICAL INVESTIGATION, 2001, 107 (05) :555-564

[6] Pancreatic gene expression in rare cells of thymic medulla: evidence for functional contribution to T cell tolerance [J].

Smith, KM ;

Olson, DC ;

Hirose, R ;

Hanahan, D .

INTERNATIONAL IMMUNOLOGY, 1997, 9 (09) :1355-1365

[7]

Sospedra M, 1998, J IMMUNOL, V161, P5918

[8] Pancreatic hormone expression in the murine thymus: Localization in dendritic cells and macrophages [J].

Throsby, M ;

Homo-Delarche, F ;

Chevenne, D ;

Goya, R ;

Dardenne, M ;

Pleau, JM .

ENDOCRINOLOGY, 1998, 139 (05) :2399-2406

← 1 →